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CURRENT Medical Diagnosis & Treatment 2024 (CMDT 2024) is the 63rd edition of this single-source reference for prac- titioners of adult medicine in both hospital and ambulatory settings. The book emphasizes the practical features of clinical diagnosis and patient management in all fields of internal medicine and in specialties of interest to primary care practitio- ners and to subspecialists who provide general care. 

With a growing recognition of systemic racism and other biases in institutions across our societies, including the institu- tion of medicine (https://www.mdcalc.com/race), the editors of CMDT, with humility, have committed to a thorough examination of our content to remove biased language, research, and recommendations. Since 2020, we have been pursuing an ongoing, formal process of review and revision in an effort to recognize and correct biases and to promote equity in our book and thus in the practice of medicine. While we, the editors, take this on as our responsibility, we also invite readers to share with us any CMDT content that they find problematic or biased. Please email comments to CMDT@mheducation.com. 

We have tried to describe populations used in the studies that form the basis of the information in CMDT and use appropriate language where we can (eg. persons of sub-Sahara African descent, rather than African Americans). We con- tinue, however, to use terms from original sources when study populations are broad. 


House officers, medical students, and all other health professions students will find the descriptions of diagnostic and therapeutic modalities, with citations to the current literature, of everyday usefulness in patient care. 

Internists, family physicians, hospitalists, nurse practitioners, physician assistants, and all primary care providers of adult medicine will appreciate CMDT as a ready reference and refresher text. Physicians in other specialties, pharmacists, and dentists will find the book a useful basic medical reference text. Nurses, nurse practitioners, and physician assistants will welcome the format and scope of the book as a means of quickly referencing medical diagnosis and treatment modalities. 

Patients and their family members who seek information about the nature of specific diseases and their diagnosis and treatment may also find this book to be a valuable resource. 


“Year in Review: Key Clinical Updates in CMDT 2024” highlights the many topics with significant clinical changes over the last year, providing page numbers and reference citations for easy access In particular, the CMDT editors wish to draw your attention! to the following changes that are likely to impact your daily 

clinical practice: 

Latest USPSTF recommendations for cardiovascular risk prevention 

Significant new opioid prescribing guidelines from the CDC 

Revisions clarifying the distinction between uncontrolled hypertension and hypertensive emergency 

Recommendations for the initiation and titration of treatment for chronic hypertension in pregnancy 

Latest classification of lymphomas released by the WHO 

Current treatment guidelines and medications for H pylori infection 

Clarification of the role, dosing, and potential risks of JAK inhibitors and anti-23 antibody (risankizumab) in the treat- ment of IBD 

Revisions that underscore the growing utility of combination treatments for high LDL. levels, especially among high-and 

very-high-risk patients 

The WHO revision of the pathologic classification of renal cell carcinoma to assist with prognosis prediction and treat- ment decisions 

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